Figure 1

Multivariate analysis of the fecal metabolome of healthy cats and cats with chronic enteropathy. (a) Heat map showing metabolites that were significantly different between healthy cats and cats with inflammatory bowel disease (IBD) and alimentary small cell lymphoma (SCL). Groups are represented by the colored bars at the top of the figure as red (healthy, n = 14), green (IBD, n = 11), and blue (SCL, n = 11). Clusters can be identified between healthy cats and cats with chronic enteropathy (CE) but not between the disease subgroups IBD and SCL. (b) PCA score plots of metabolites in feces from healthy cats (green) and cats with chronic enteropathy (CE, red). (c) PCA score plots of metabolites in feces from healthy cats (red), cats with inflammatory bowel disease (blue), and cats with alimentary small cell lymphoma (green). A cluster can be identified for healthy cats but no specific clusters can be seen for the subgroups of IBD and SCL. Data was mean centered and divided by the standard deviation of each variable (autoscaled).