Table 1 Comparisons between different cut-off values of PD-ENE.

From: Prognostic value of extranodal extension in axillary lymph node-positive breast cancer

Cut-off values

No. of patients (%)

Sensitivity (%)

Specificity (%)

Youden’s index

PD-ENE for DFS

1 mm

37.3

76.47

29.03

0.055

2 mm

22.7

41.18

66.94

0.081

3 mm

6.3

8.82

87.1

− 0.041

PD-ENE for OS

1 mm

37.3

69.23

35.61

0.048

2 mm

22.7

92.31

12.88

0.052

3 mm

6.3

96.15

6.06

0.022

CD-ENE for DFS

1 mm

15.8

97.06

13.71

0.107

2 mm

26.5

82.35

29.84

0.122

3 mm

18.3

58.82

57.26

0.161

4 mm

5.6

20.59

70.16

− 0.093

CD-ENE for OS

1 mm

15.8

23.08

71.97

− 0.050

2 mm

26.5

53.85

46.21

0.060

3 mm

18.3

88.46

31.06

0.195

4 mm

5.6

88.46

24.24

0.127

  1. PD-ENE perpendicular diameter of extra-nodal extension; CD-ENE circumferential diameter of extra-nodal extension; DFS disease recurrence free survival; OS overall survival; Youden’s Index = sensitivity + specificity − 1. The values in italic are the maximum Youden's index.