Figure 3
From: Direct conversion of porcine primary fibroblasts into hepatocyte-like cells
Second step of transcription factor screening in PKFs. Albumin secretion (upper panel), ALBUMIN and A1AT gene expression levels (medium and lower panel, respectively) in PKFs transduced with 12 TFs minus families of factors such as the FOXAs, GATAs and HNF1α; HNF1β. All data were analyzed using one-way ANOVA, with Tukey’s post-test. Significance from n = 6 independent values is displayed as *p < 0.05; ****p ≤ 0.0001.
