Table 1 Baseline characteristics of patients and lesions.

From: Non-randomized comparison between revascularization and deferral for intermediate coronary stenosis with abnormal fractional flow reserve and preserved coronary flow reserve

 

Total

PCI

Deferred

P value

Per-patient analysis (n = 330)

330

231

99

 

Demographics

Age

64.3 ± 9.7

65.1 ± 9.7

62.3 ± 9.3

0.016

Female

37 (11.2)

25 (10.8)

12 (12.1)

0.879

Cardiovascular risk factors

Hypertension

220 (66.7)

151 (65.4)

69 (69.7)

0.524

Diabetes mellitus

109 (33.0)

81 (35.1)

28 (28.3)

0.283

Hyperlipidemia

225 (68.2)

157 (68.0)

68 (68.7)

1.000

Current smoker

74 (22.4)

51 (22.1)

23 (23.2)

0.931

Family history of CAD

30 (9.9)

21 (10.1)

9 (9.5)

1.000

Clinical presentation

0.297

Acute coronary syndrome

39 (11.8)

24 (10.4)

15 (15.2)

 

Stable ischemic heart disease

291 (88.2)

207 (89.6)

84 (84.9)

 

Per-vessel analysis (n = 338)

338

233

105

 

Target vessel location

0.014

Left anterior descending artery

274 (81.3)

182 (78.1)

92 (88.5)

 

Left circumflex artery

20 (5.9)

13 (5.6)

7 (6.7)

 

Right coronary artery

43 (12.8)

38 (16.3)

5 (4.8)

 

Quantitative coronary angiography

Reference vessel diameter, mm

2.77 (2.38–3.15)

2.75 (2.37–3.13)

2.88 (2.38–3.19)

0.597

Minimal luminal diameter, mm

1.26 (1.01–1.56)

1.17 (0.94–1.43)

1.48 (1.17–1.71)

 < 0.001

Diameter stenosis, %

53.8 ± 13.6

56.7 ± 13.0

47.7 ± 12.8

 < 0.001

Lesion length, mm

12.56 (8.00–19.68)

13.24 (8.55–20.35)

10.00 (6.16–18.06)

0.026

Invasive physiologic indices

FFR, Pre-PCI

0.75 (0.71–0.78)

0.74 (0.69–0.77)

0.78 (0.75–0.79)

 < 0.001

CFR, Pre-PCI

3.00 (2.50–3.80)

2.96 (2.50–3.54)

3.14 (2.58–3.90)

0.065

  1. Values are mean ± standard deviations, median (interquartile range), or number (%).
  2. CAD Coronary artery disease, CFR Coronary flow reserve, FFR Fractional flow reserve, PCI Percutaneous coronary intervention.