Table 1 Baseline characteristics of patients and lesions.
Total | PCI | Deferred | P value | |
---|---|---|---|---|
Per-patient analysis (n = 330) | 330 | 231 | 99 | |
Demographics | ||||
Age | 64.3 ± 9.7 | 65.1 ± 9.7 | 62.3 ± 9.3 | 0.016 |
Female | 37 (11.2) | 25 (10.8) | 12 (12.1) | 0.879 |
Cardiovascular risk factors | ||||
Hypertension | 220 (66.7) | 151 (65.4) | 69 (69.7) | 0.524 |
Diabetes mellitus | 109 (33.0) | 81 (35.1) | 28 (28.3) | 0.283 |
Hyperlipidemia | 225 (68.2) | 157 (68.0) | 68 (68.7) | 1.000 |
Current smoker | 74 (22.4) | 51 (22.1) | 23 (23.2) | 0.931 |
Family history of CAD | 30 (9.9) | 21 (10.1) | 9 (9.5) | 1.000 |
Clinical presentation | 0.297 | |||
Acute coronary syndrome | 39 (11.8) | 24 (10.4) | 15 (15.2) | |
Stable ischemic heart disease | 291 (88.2) | 207 (89.6) | 84 (84.9) | |
Per-vessel analysis (n = 338) | 338 | 233 | 105 | |
Target vessel location | 0.014 | |||
Left anterior descending artery | 274 (81.3) | 182 (78.1) | 92 (88.5) | |
Left circumflex artery | 20 (5.9) | 13 (5.6) | 7 (6.7) | |
Right coronary artery | 43 (12.8) | 38 (16.3) | 5 (4.8) | |
Quantitative coronary angiography | ||||
Reference vessel diameter, mm | 2.77 (2.38–3.15) | 2.75 (2.37–3.13) | 2.88 (2.38–3.19) | 0.597 |
Minimal luminal diameter, mm | 1.26 (1.01–1.56) | 1.17 (0.94–1.43) | 1.48 (1.17–1.71) | < 0.001 |
Diameter stenosis, % | 53.8 ± 13.6 | 56.7 ± 13.0 | 47.7 ± 12.8 | < 0.001 |
Lesion length, mm | 12.56 (8.00–19.68) | 13.24 (8.55–20.35) | 10.00 (6.16–18.06) | 0.026 |
Invasive physiologic indices | ||||
FFR, Pre-PCI | 0.75 (0.71–0.78) | 0.74 (0.69–0.77) | 0.78 (0.75–0.79) | < 0.001 |
CFR, Pre-PCI | 3.00 (2.50–3.80) | 2.96 (2.50–3.54) | 3.14 (2.58–3.90) | 0.065 |