Table 4 Description of tropism changes at T1 and T2: patients are classified according to X4 tropic or R5 tropic virus infection at baseline.

From: HIV tropism switch in archived DNA of HIV-HCV subjects successfully treated with direct-acting antivirals for HCV infection

 

HIV RNA control

Tropism at BL

Tropism at T1

Tropism at T2

Patients with X4 infection at baseline

Patient 1

UV

X4

X4

R5

Patient 2

RV

X4

X4

R5

Patient 3

RV

X4

R5

X4

Patient 4

RV

X4

X4

R5

Patient 5

RV

X4

X4

R5

Patients with R5 infection at baseline

Patient 1

UV

R5

X4

X4

Patient 2

UV

R5

R5

X4

Patient 3

RV

R5

X4

R5

Patient 4

RV

R5

X4

X4

Patient 5

RV

R5

X4

R5

Patient 6

RV

R5

X4

X4

Patient 7

RV

R5

X4

X4

Patient 8

RV

R5

X4

X4

Patient 9

RV

R5

X4

X4

  1. Bold characters correspond to tropism modification respect to BL.
  2. RV residual HIV viremia, UV undetectable HIV viremia, BL baseline, T1 week 12 of anti HCV treatment, T2 week 24 after HCV treatment start.