Table 5 Description of tropism results obtained with the conventional rule (FPR < 10% corresponding to X4 tropic virus) and with the mean FPR value (mFv) rule (mean FPR value of the three sequences performed for each tropism determination < 10% corresponding to X4 tropic virus).

From: HIV tropism switch in archived DNA of HIV-HCV subjects successfully treated with direct-acting antivirals for HCV infection

Conventional rule

BL

Conventional rule

T1

Conventional rule

T2

mFv rule

BL

mFv rule

T1

mFv rule

T2

Tropism changes with mFV rule

Number of changes with mFV rule

Tropism switches with conventional rule

Tropism switches with mFV rule

R5

X4

R5

R5

R5

R5

From X4 to R5 at T1

1

Yes

NO

X4

X4

X4

X4

X4

R5

From X4 to R5 at T2

1

No

YES

R5

X4

X4

R5

R5

R5

From X4 to R5 at T1 and T2

2

Yes

NO

X4

X4

X4

R5

X4

R5

From X4 to R5 at BL and T2

2

No

YES

X4

X4

X4

R5

R5

X4

From X4 to R5 at BL and T1

2

No

YES

R5

X4

X4

R5

R5

R5

From X4 to R5 at T1 and T2

2

Yes

NO

X4

X4

X4

R5

X4

X4

From X4 to R5 at BL

1

No

YES

X4

X4

R5

R5

X4

R5

From X4 to R5 at BL

1

Yes

yes

X4

X4

R5

R5

X4

R5

From X4 to R5 at BL

1

Yes

yes

X4

X4

X4

X4

R5

R5

From X4 to R5 at T1 and at T2

2

No

YES

X4

X4

X4

R5

R5

X4

From X4 to R5 at BL and at T1

2

No

YES

X4

X4

R5

R5

R5

R5

From X4 to R5 at BL and at T1

2

Yes

NO

R5

X4

X4

R5

R5

R5

From X4 to R5 at T1 and at T2

2

Yes

NO

R5

X4

X4

R5

R5

X4

From X4 to R5 at T1

1

Yes

yes

X4

X4

X4

R5

X4

X4

From X4 to R5 at BL

1

No

YES

  1. Capital letters were used to describe a different tropism evolution throughout study time when mFv rule is applied.