Figure 6
From: Cytochrome P450-epoxygenated fatty acids inhibit Müller glial inflammation
The effect of 11,12-EET or 19,20-EDP on PA or IL-1β-induced NFκB promoter activity. hMC were transfected with a NFκB-luciferase reporter construct and treated with (a) PA (b) IL-1β or in the presence or absence of 11,12-EET (0.5 μM) or 19,20-EDP (0.5 μM). NFκB activity was determined by measuring the ratio of firefly-to-renilla luciferase luminescence activity. Each bar represents the mean ± SD (n = 4, 5 or 6).
