Figure 6
From: Mechanical biofilm disruption causes microbial and immunological shifts in periodontitis patients
Investigating the subgingival plaque microbiome in relation to treatment response. (A) Comparing the pocket depth of sampled sites at baseline (BL) and day 90 (D90) depending on whether pocket closure was achieved (n = 21) or not achieved (n = 19) post-treatment. Dotted black line indicates 5 mm. Between group comparisons refer to unpaired t-tests (ns: non-significant, ***p < 0.001), within-group comparisons refer to paired t-tests (†p < 0.001), graphs display mean ± 95% confidence interval. (B) Species-level Bray–Curtis based PCoA analysis of each group at baseline, statistics are PERMANOVA with raw p-value displayed. (C) Comparing Bray–Curtis similarity with baseline between groups, statistics refer to Mann–Whitney test, ns: non-significant. (D) Plotting the top 30 most abundant species at BL and D90 between groups, No; pocket closure not achieved, Yes; pocket closure achieved.
