Figure 7
From: Mechanical biofilm disruption causes microbial and immunological shifts in periodontitis patients
Levels of local inflammatory markers in saliva. (A) Correlating the levels of salivary inflammatory markers at baseline with clinical periodontal parameters, values represent Spearman-Rho correlation. P-values were corrected using FDR (5%) where *p(adjusted) < 0.05 and **p(adjusted) < 0.01. Confidence intervals are supplied in supplementary dataset 1 (B) Comparing changes in the levels of TNFα, IL-6, IL-8, IL-17A and IL-1β at baseline (BL) and day-90 (D90). Graphs are Tukey boxplots where horizontal line indicates the median and individual points indicate potential outliers. Statistics are Wilcoxon signed rank test, where ***p < 0.001. n = 41. (C) Pearson’s correlation between change in PISA and change in salivary cytokines, raw p-values are shown.
