Table 1 Demographic, clinical and MRI features of the three groups evaluated.

From: Volumetric and shape analysis of the hippocampus in temporal lobe epilepsy with GAD65 antibodies compared with non-immune epilepsy

Characteristics

GAD-TLE (8)

niTLE (8)

HC (8)

Median age at MRI (IQR) (years)

37.3 (5.9)

37.1 (30)

34 (8.5)

Median age at onset (IQR) (years)

29 (5.5)

9 (11.5)

N/A

Duration of Epilepsy Me (IQR)

7.9 (8.6)

16.9 (24.7)

N/A

Sex (n; %)

Female

6 (75)

7 (87.5)

5 (62.5)

Male

2 (25)

1 (12.5)

3 (37.5)

Autoimmune comorbidities n (%)

6 (54.5)

0

0

Education n (%)

Primary education

1 (12.5)

4 (50%)

N/A

Secondary education

1 (12.5)

2 (25%)

 

University education

6 (75)

2(25%)

 

Handedness n (%)

Right dominance

8 (100)

7 (87.5)

8 (100)

Hippocampal sclerosis n (%)

3 (37.5)

8 (100)

 

Right

1

1

N/A

Left

0

7

 

Bilateral

2

0

 

Type of TLE n (%)

Unilateral

   

Right

2 (25)

2 (25)

 

Left

4 (50)

6 (75)

N/A

Bilateral

2(25)

0 (0)

 

Seizure frequency at onset n (%)

Daily

3 (37.5)

0

N/A

Weekly

2 (25)

1 (12.5)

 

Monthly

3 (37.5)

7 (87.5)

 

Seizure type

FAS and FIAS

7 (87.5)

8 (100)

N/A

FBTCS

1 (12.5)

0 (0)

 

Present ASM median (IQR)

3 (1)

3 (2)

N/A

Prior ASM median (IQR)

4.5 (1.5)

2.5 (1)

N/A

  1. TLE temporal lobe epilepsy, FAS focal aware seizures, FIAS focal impaired awareness, FBTCS focal to bilateral tonic–clonic seizure, ASM antiseizure medication, Me median, IQR interquartile range, N/A not applicable.