Figure 5 | Scientific Reports

Figure 5

From: Multi-step screening of neoantigens’ HLA- and TCR-interfaces improves prediction of survival

Figure 5

Effect of Ancer's neoepitope and homology filters on survival analyses. Ancer neoepitope and homology filters improve association with disease free survival (DFS) (a) and overall survival (OS) (b). Hazard ratios (HR), confidence intervals (CI) and p-values (p) were calculated using univariate Cox proportional-hazard models. BCLA patients were separated based on their Ancer neoepitope burden (Ancer, all steps), similarly to Fig. 3, "non-matching" Ancer neoepitope burden without considering the JanusMatrix filter (Ancer, steps 1–2), or based on their "raw" Ancer neoepitope burden (Ancer, step 1 only).

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