Table 2 Results of the association analysis between clinical signs (swollen/painful) and gene expression in subsets of monocytes.

From: Expression of VEGFA-mRNA in classical and MSX2-mRNA in non-classical monocytes in patients with spondyloarthritis is associated with peripheral arthritis

Gene

Monocyte subset

Number of joints

FDR

logFC

VEGFA

Classical

Swollen (total)

0.043

− 0.448

VEGFA

Classical

Painful (total)

0.191

− 0.412

VEGFA

Classical

Swollen (DAS28)

 < 0.001

− 0.674

VEGFA

Classical

Painful (DAS28)

0.008

− 0.704

MSX2

Non-classical

Swollen (total)

0.002

− 0.956

MSX2

Non-classical

Painful (total)

0.083

− 0.906

MSX2

Non-classical

Swollen (DAS28)

 < 0.001

− 1.072

MSX2

Non-classical

Painful (DAS28)

0.008

− 1.131

  1. The false discovery rate (FDR) was estimated for each clinical variable separately due to small sample size.
  2. FDR estimated false discovery rate based on all tests performed, logFC logarithm of the fold change of the expression levels between experimental conditions.
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