Figure 3

Biological process network analysis of differentially regulated urine proteins in KA. (A) KEGG pathway map for the complement and coagulation cascades identified as the top pathway enriched from a proportion of differentially expressed proteins (protein count = 20, denoted by asterisks). (B) Protein–protein interaction networks for 46 fibrosis-related proteins analyzed using STRING (PPI enrichment p-value < 10e−16, average local clustering coefficient of 0.583). Line thickness indicates the strength of data support.