Figure 5 | Scientific Reports

Figure 5

From: Skeletal muscle metabolic responses to physical activity are muscle type specific in a rat model of chronic kidney disease

Figure 5

Mitochondrial content is decreased in soleus of CKD wheel running rats. (a) The slow-twitch soleus muscle demonstrated a disease-related reduction in complex I subunit, where CKD was lower than normal; no additional mitochondrial complex markers were different between NL and CKD. However, CKD-wheel rats demonstrated lower mitochondrial content for complexes I-IV subunits when compared to NL rats; only the complex III subunit demonstrated a CKD vs CKD-W difference. (b) Representative OXPHOS blots are provided with manipulated figures to unique exposures times per individual complex. Data are shown as mean ± SD (n = 9 rats each group). *P < 0.05, **P < 0.01.

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