Figure 6
Mitochondrial content is decreased in the EDL of CKD wheel running rats. (a) The fast-twitch EDL demonstrated no differences in mitochondrial content markers between NL and CKD rats across complexes I-V subunits. However, when CKD rats performed wheel running, mitochondrial content markers were significantly lower for complex I-IV subunits when compared to NL rats. When comparing CKD to CKD-W, mitochondrial complexes I and IV subunits were lower in CKD-W. (b) Representative OXPHOS blots are provided with manipulated figures to unique exposures times per individual complex. Data are shown as mean ± SD (n = 9 rats each group). *p < 0.05, **p < 0.01.
