Figure 2

Bioluminescence images of NSG mice (LL/2 or B16F10) intravenously injected with PEG-fluc FNC particle. At 7 d post injection of the LL/2 tumor cells or 14 d post injection of B16F10 tumor cells, mice were injected with reconstituted FNC particles expressing firefly luciferase. Mice were imaged 48Â h post injection of the particles with IVIS Spectrum In Vivo Imaging System. Ventral (A, C, E) and dorsal (B, D, F) views of the same mice are shown for the non-tumor bearing mice (A, B), LL/2 (C, D), and B16F19 (E, F) mice.