Figure 6 | Scientific Reports

Figure 6

From: A study of deregulated MMR pathways and anticancer potential of curcuma derivatives using computational approach

Figure 6

Schematic representation of possible implication of curcuma derivatives in activation of MMR system. (A) Shows compounds (91, 88, and 3) of C. caesia Roxb. interacting with their primary targets (abl1, max, myb, blm, myc, p73) which impact the MMR proteins (msh2, msh5, msh6, mlh1, pms2). (B) Depicts interactions that occur between the compounds (EF31, UBS109, and Bisacurone) of C. longa L. with their primary targets (pcna, myb, top3a) which further modulate MMR proteins (msh2, msh3, msh6, msh5, mlh1).

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