Figure 2 | Scientific Reports

Figure 2

From: Impact of intrauterine fetal resuscitation with oxygen on oxidative stress in the developing rat brain

Figure 2

Oxidative stress biomarkers in the fetal brain after maternal hyperoxia. Scatter plots showing the extent of oxidative damage to lipids, proteins, and DNA as quantified by 4-hydroxynonenal (A), protein carbonyl (B), and 8-OHdG (C), respectively. Maternal hyperoxia was not associated with an increase in any of the biomarkers in either sex. The GSSG/GSH ratio (D), indicative of the collective glutathione antioxidant response, was no different between the groups. Data are presented as mean ± S.E.M and analyzed with 2-way ANOVA with Sidak’s multiple comparisons test to assess for sex differences in the treated group (n = 8 male and female pups from 8 unique dams/treatment condition).

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