Table 2 Hemodynamics, pulmonary mechanics, blood gas data, and preload indicators for each time interval.

HR (beats/min)

118 (22)

100 (31)

116 (22)

114 (21)

109 (21)*

SAP (mmHg)

136.9 (30.3)

134.8 (29.4)

123.2 (27.1)^a,b

125.2 (25.1)

128.9 (21.5)

MAP (mmHg)

86.7 (20.9)

86.0 (19.9)

79.2 (20.1)^a,b

81.5 (19.9)

85.2 (16)

CI (L/min/^.m²)

3.88 (1.16)

3.78 (1.07)

3.66 (1.10)^a

3.59 (1.09)

4.23 (1.31)*

SVI (mL/m²)

33.3 (8.8)

33.2 (8.2)

31.7 (8.6)^a

31.6 (8.1)

38.5 (8.6)*

SVRI (dynes/sec/cm⁵/m²)

1555 (453)

1592 (507)

1479 (420)^b

1549 (392)

1344 (535)*

Pplat (cmH₂O)

20.4 (4.3)

24.32 (4.7)^c

31.39 (5.3)^a,b

30.36 (6.2)

29.96 (6.1)

Pmean (cmH₂O)

10.39 (1.7)

15.13 (2.4)^c

20.69 (2.1)^a,b

19.6 (3.1)

19.7 (3.2)

Total PEEP (cm/H₂O)

6.15 (1.1)

10.67 (0.8)^c

15.54 (0.8)^a,b

14.5 (1.5)

14.7 (1.6)

Crs (mL/cmH₂O)

32.1 (14.8)

35.3 (15.0)

29.8 (14.1)^b

29.9 (11.9)

30.5 (12.7)

Driving pressure (Pplat-total PEEP) (cm/H₂O)

14.25 (4.3)

13.6 (4.9)

15.86 (5.4)^b

15.9 (5.9)

15.3 (5.9)

SVV (%)

8.5 (5.4)

9.3 (5.3)

12.8 (7.2)^a,b

11.6 (6.8)

7.8 (4.9)*

PPV (%)

5.9 (3.8)

6.2 (3.3)

9.7 (5.0)^a,b

9.5 (5.4)

5.7 (3.3)*

PPV/driving-P (%)

0.46 (0.32)

0.52 (0.4)

0.68 (0.42)^a,b

0.63 (0.38)

0.54 (0.69)*

PPV/Crs (%)

0.22 (0.18)

02.0 (0.12)

0.39 (0.27)^a,b

0.38 (0.29)

0.24 (0.19)*

PaO₂ mmHg

64.9 (17.3)

85.6 (31.1)^c

89.2 (42.3)^a

PaO₂/FiO₂

109.2 (54.5)

138.7 (57)^c

143.8 (63.8)^a

PaCO₂ mmHg

60.8 (19.9)

60.9 (20.5)

62.4 (20)

SaO₂ (%)

86.0 (8.9)

92.5 (5.6)^c

92.7 (5.0)^a