Table 4 Predictive performance of fluid responsiveness for PPV, SVV, PPV/driving-P, and PPV/Crs among the three PEEP levels.

From: Effects of positive end-expiratory pressure on the predictability of fluid responsiveness in acute respiratory distress syndrome patients

 

PPV

SVV

PPV/driving-P

PPV/Crs

PEEP 5

AUC

0.81 (0.61–0.93)

0.75 (0.55–0.90)

0.75 (0.55–0.90)

0.76 (0.55–0.90)

Cutoff

3.2

4.5

0.26

0.1

Sensitivity (%)

100 (79.4–100)

100 (79.4–100.0)

87.5 (61.7–98.4)

93.6 (69.8–99.8)

Specificity (%)

54.6 (23.4–83.3)

54.6 (23.4–83.3)

63.6 (30.8–89.1)

54.6 (23.4–83.3)

PEEP 10

AUC

0.67 (0.46–0.84)

0.79 (0.59–0.92)

0.72 (0.52–0.88)

0.67 (0.47–0.84)

Cutoff

4.6

10.4

0.42

0.15

Sensitivity (%)

75 (47.6–92.7)

50 (24.7–75.3)

62.5 (35.4–84.8)

68.8 (41.3–89.0)

Specificity (%)

63.6 (30.8–89.1)

100 (71.5–100)

81.8 (48.2–97.7)

63.6 (30.8–89.1)

PEEP 15

AUC

0.85 (0.66–0.96)

0.76 (0.55–0.90)

0.88 (0.69–0.97)

0.71 (0.50–0.86)

Cutoff

8.8

11.5

0.48

0.32

Sensitivity (%)

75 (47.6–92.7)

62.5 (35.4–84.8)

81.3 (54.5–96.0)

68.8 (41.3–89.0)

Specificity (%)

90.9 (58.7–99.8)

100 (71.5–100)

90.9 (58.7–99.8)

72.7 (39.0–94.0)

  1. AUC area under the receiver operating characteristic curve, PPV pulse pressure variation, SVV stroke volume variation, Crs respiratory system compliance.