Table 3 DAS28-ESR components in the ACarPA+ patients relative to the ACarPA− EA patients at baselinea.
From: Increased disease activity in early arthritis patients with anti-carbamylated protein antibodies
Component/Adjustment | βb | SE | p value | ACarPA+ EMM | ACarPA− EMM |
---|---|---|---|---|---|
Swollen Joint Count | |||||
noc | 0.18 | 0.03 | 3.02 × 10–8 | 4.80 (4.20–5.43) | 2.99 (2.69–3.28) |
basicc | 0.18 | 0.03 | 1.28 × 10–8 | 4.80 (4.20–5.43) | 2.96 (2.66–3.31) |
basic + CCPc | 0.12 | 0.03 | 0.0004 | 4.49 (3.92–5.15) | 3.28 (2.92–3.69) |
basic + RFc | 0.14 | 0.03 | 0.00005 | 4.58 (3.96–5.24) | 3.17 (2.79–3.53) |
basic + CCP & RFc | 0.12 | 0.03 | 0.0008 | 4.49 (3.88–5.15) | 3.31 (2.92–3.69) |
Tender Joint Count | |||||
noc | 0.16 | 0.03 | 1.01 × 10–6 | 5.76 (4.97–6.60) | 3.65 (3.24–4.04) |
basicc | 0.14 | 0.03 | 4.25 × 10–6 | 5.11 (4.37–5.95) | 3.28 (2.86–3.69) |
basic + CCPc | 0.13 | 0.03 | 0.0002 | 5.02 (4.24–5.86) | 3.39 (2.96–3.88) |
basic + RFc | 0.12 | 0.03 | 0.0003 | 4.97 (4.20–5.81) | 3.39 (2.96–3.88) |
basic + CCP & RFc | 0.12 | 0.03 | 0.0006 | 4.97 (4.20–5.81) | 3.42 (2.96–3.92) |
Patient Global Assessment | |||||
noc | 0.09 | 0.03 | 0.006 | 48.21 (45.18–51.25) | 43.17 (41.27–45.07) |
basicc | 0.08 | 0.03 | 0.01 | 47.0 (43.79–50.20) | 43.34 (40.22–44.46) |
basic + CCPc | 0.06 | 0.03 | 0.07 | 46.54 (43.27–49.80) | 42.97 (40.68–45.27) |
basic + RFc | 0.08 | 0.03 | 0.02 | 46.97 (43.67–50.27) | 42.37 (40.10–44.64) |
basic + CCP & RFc | 0.07 | 0.04 | 0.049 | 46.78 (43.47–50.08) | 42.81 (40.49–45.13) |
Erythrocyte Sedimentation Rate | |||||
noc | 0.12 | 0.03 | 0.0001 | 27.11 (24.53–29.96) | 21.33 (20.09–22.87) |
basicc | 0.12 | 0.03 | 0.00006 | 24.78 (22.20–27.39) | 19.49 (18.54–20.91) |
basic + CCPc | 0.07 | 0.03 | 0.044 | 23.57 (21.33–26.31) | 20.70 (19.30–22.42) |
basic + RFc | 0.08 | 0.03 | 0.015 | 23.81 (21.33–26.58) | 20.29 (18.92–21.98) |
basic + CCP & RFc | 0.06 | 0.03 | 0.067 | 23.57 (21.12–26.05) | 20.91 (19.30–22.42) |