Figure 3 | Scientific Reports

Figure 3

From: Easy ultrastructural insight into the internal morphology of biological specimens by Atomic Force Microscopy

Figure 3

AFM-based ultrastructural analysis of exemplary mammalian tissues. Nanoscopic resolution on more complex tissues. (a) AFM amplitude data of an ultra-section of human knee cartilage. (b) High resolution close up on single collagen fibrils. Note the preservation as well as the clear resolution of the characteristic 67 nm D-periodicity of single collagen fibrils. (c) Height data depiction of an ultra-section from human melanoma tissue. (d) AFM height data of a mouse kidney ultra-section showing a single glomerulus as well as surrounding tubuli. Scale bars (a) 2 µm, (b) 840 nm, (c) 6 µm, (d) 10 µm. N nucleus, NM nuclear membrane, Nuc nucleolus.

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