Table 2 List of genes targeted by transcription factor genes.

From: Osteocytes as main responders to low-intensity pulsed ultrasound treatment during fracture healing

Transcription genes

Target genes

Average score

Expression level in MLO-Y4

(FPKM value)

Significant

Function

Refs.

LIPUS −

LIPUS + 

Egr1

Greb1

1109.833333

1.53125

1.21937

no

  

Olfr806

790.5

n.d

n.d

no

  

Abhd6

774.166667

1.07994

0.848552

no

  

Wwox

725.666667

6.25733

5.4122

no

  

Aadacl2fm1

613.666667

n.d

n.d

no

  

Nkx2-6

581.5

n.d

n.d

no

  

Setd4

549.333333

0.960806

0.709573

no

  

Cbr1

549.333333

31.0524

28.1055

no

Carbonyl reductases, Catalyst for the reduction of endogenious prostaglandine and steroids

24

Cldn34d

526.666667

n.d

n.d

no

  

Tecpr1

434.166667

2.83544

3.10746

no

  

Egr2

Dynlt1b

756

34.0942

34.2265

no

Activators of G-protein signaling

PMID: 11358340

Lcmt1

749.909091

8.62011

10.0269

no

  

Arhgap17

749.909091

15.6857

17.1241

no

Rho GTPase activating proteins, Maintenance of tight junctions

PMID: 16678097

Ncapg2

746.181818

27.2157

32.8379

no

A component of the chromosome condension II complex, which is critical for mitosis

PMID: 31176678

Mtrf1l

740.818182

3.14548

5.9366

no

  

Sdhaf3

712.454545

0.920439

1.18144

no

  

D10Wsu102e

690.090909

1.87224

1.91581

no

  

Cenpu

677.818182

15.7252

21.934

no

  

Cplane1

676.272727

6.84822

5.60805

no

  

Cmtm6

647.636364

7.80277

9.01462

no

  

Nr4a1

Adssl1

811.428571

24.6413

38.4503

no

Adenylosuccinate synthetase, which catalyzes AMP synthesis

PMID: 15786719

Mcl1

809.285714

126.123

156.683

no

Anti-apoptotic protein, pro-survival protein

PMID: 20023629

Txk

800.285714

n.d

n.d

no

  

Tmem179

767.428571

1.11521

4.11481

no

  

Cpm

706.142857

3.52267

3.59489

no

  

Greb1

679.428571

1.53125

1.21937

no

  

Olfr266

655

n.d

n.d

no

  

Rapgef2

630.285714

5.72616

5.78346

no

  

Cst3

607.857143

454.443

593.939

no

Cysteine proteinase inhibitor, An inhibitor of bone resorption

25

Brox

606.285714

15.5085

15.461

no

Apoptosis-linked gene, Controlling of cell death through the regulation of the endolysosomal system

PMID: 16407552

JunB

Cldn34d

895.351351

n.d

n.d

no

  

Brox

763.783784

15.5085

15.461

no

Apoptosis-linked gene, Controlling of cell death through the regulation of the endolysosomal system

PMID: 16407552

Aida

763.783784

67.1444

55.861

no

Axin-interacting protein, Blocking Axin/JNK signaling

 

Cdc42bpg

643.567568

5.53688

6.65211

no

  

Mefv

604.567568

n.d

n.d

no

  

Ank1

598.972973

7.66976

6.28425

no

  

Prss56

598.027027

0

0.216514

no

  

Chrnd

598.027027

n.d

n.d

no

  

Cass4

595.810811

0.0982373

0.0633786

no

  

Htra3

574.432432

10.6126

13.0335

no

Serine protease, An inhibitor of TGF-b signaling

23

Nfatc1

Greb1

1166

1.53125

1.21937

no

  

Olfr855

844.333333

n.d

n.d

no

  

Olfr854

844.333333

n.d

n.d

no

  

Abhd6

796.333333

1.07994

0.848552

no

  

Nkx2-6

765.333333

n.d

n.d

no

  

Wwox

748.333333

6.25733

5.4122

no

  

Olfr806

723

n.d

n.d

no

  

Acacb

657.666667

0.787511

0.493981

no

  

Prl3c1

591.666667

n.d

n.d

no

  

Setd4

562.333333

0.960806

0.709573

no

  

Btg2

N/A

Snai2

Cited2

FoxQ1

Helz

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