Figure 3

HFD-induced foam cell formation was inhibited by dietary linseed oil. Mice were fed with either control diet with soybean oil, HFD with soybean oil or HFD with linseed oil for 10 months, and histological sections of aortic valve were examined by staining with indicated antibody and reagents. Data are representative of 2 independent experiments (n = 5/group/experiment). Arrows indicate the development of foam cells. Scale bars 20 μm.