Table 2 Protective role of bilirubin against variety of cellular stresses in endothelial cells.
Cell type | BR concentration | Effect | References |
|---|---|---|---|
Human coronary artery endothelial cells | 1, 5, and 10 µM BR | Preincubation of HCAECs with BR protects against TNF-α-mediated endothelial inflammation | |
Human glomerular endothelial cell | 10 µM | BR significantly attenuates vascular endothelin-1 release in placental ischemia model | |
Bovine aortic endothelial cells | 0.5 µM | BR protects endothelial cells against high glucose-induced damage | |
Human aortic endothelial cells | 5 µM | BR attenuates vascular endothelial activation and dysfunction | |
Cerebral microvascular endothelial cells | 1 µM | BR prevents TNF-α-induced apoptosis |
