Table 1 Demographics of the study participants.

From: Combination of automated brain volumetry on MRI and quantitative tau deposition on THK-5351 PET to support diagnosis of Alzheimer’s disease

 

HC

MCI

AD

P value

N

32

55

26

 

Age (years)

69.4 ± 6.0

70.8 ± 7.1

63.6 ± 10.6

0.001

Sex (M/F)

11/21

20/35

11/15

0.816

Education (years)

10.6 ± 4.9

11.1 ± 4.6

10.6 ± 4.7

0.846

APOE ε4 (0/1/2)a

(24/7/0)

(NA 1)

(28/17/5)

(NA 5)

(14/6/2)

(NA 4)

0.082

K-MMSE score

28.6 ± 1.2

25.0 ± 3.2

19.9 + 5.0

 < 0.001

Days between MRI and [18F] THK-5351 scan

47.5 ± 35.6

57.1 ± 50.1

53.6 ± 47.0

0.659

  1. HC, healthy controls; MCI, mild cognitive impairment; AD, Alzheimer disease; K-MMSE, Korean version of the Mini-Mental State Examination.
  2. a0/1/2 indicates non-carriers/heterozygotes/homozygotes for APOE ε4 respectively.
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