Table 2 Univariate and multivariate logistic regression analysis of automated volumes on MRI for discriminating AD from HC and MCI.
Variable | AD vs. HC | AD vs. MCI | ||||||
|---|---|---|---|---|---|---|---|---|
Univariate analysis | Multivariate analysis | Univariate analysis | Multivariate analysis | |||||
β coefficient (95% CI) | P value | β coefficient (95% CI) | P value | β coefficient (95% CI) | P value | β coefficient (95% CI) | P value | |
Hippocampus | − 1.07 (− 1.76, − 0.51) | < 0.001 | − 0.06 (− 0.46, 0.33) | 0.782 | ||||
Entorhinal cortex | − 0.79 (− 1.46, − 0.25) | 0.012 | − 0.30 (− 0.74, 0.11) | 0.172 | ||||
Superior temporal | − 0.14 (− 0.31, − 0.001) | 0.061 | − 0.02 (− 0.13, 0.08) | 0.681 | 0.15 (0.0009, 0.32) | 0.062 | ||
Middle temporal | − 0.34 (− 0.58, − 0.15) | 0.002 | − 0.12 (− 0.25, 0.005) | 0.072 | ||||
Anterior cingulate | − 0.89 (− 1.62, − 0.26) | 0.013 | − 0.89 (− 1.57, − 0.28) | 0.006 | − 0.70 (− 1.50, 0.04) | 0.072 | ||
Posterior cingulate | − 1.39 (− 2.51, − 0.48) | 0.006 | − 1.49 (− 2.51, − 0.63) | 0.001 | ||||
Cingulate isthmus | − 1.88 (− 3.13, − 0.92) | < 0.001 | − 2.64 (− 5.10, − 1.01) | 0.009 | − 1.22 (− 2.04, − 0.50) | 0.002 | − 0.94 (− 1.90, − 0.05) | 0.041 |
Anterior middle frontal | − 0.38 (− 0.72, − 0.10) | 0.011 | − 0.18 (− 0.45, 0.05) | 0.152 | ||||
Inferior parietal lobule | − 0.52 (− 0.84, − 0.28) | < 0.001 | − 0.53 (− 1.07, − 0.15) | 0.022 | − 0.31 (− 0.50, − 0.14) | 0.001 | − 0.27 (− 0.50, − 0.07) | 0.012 |
Supramarginal | − 0.79 (− 1.27, − 0.43) | < 0.001 | − 0.56 (− 1.25, − 0.04) | 0.061 | − 0.18 (− 0.40, 0.01) | 0.081 | ||
