Table 2 Cox model measured hazard ratios and 95% confidence interval of fibromyalgia associated with iron deficiency anemia and covariates.
Variable | Event no | Person-years | Incidence density# | HR (95%CI) | |
|---|---|---|---|---|---|
Unadjusted | Adjusted† | ||||
Iron deficiency anemia | |||||
No | 3014 | 102,479 | 29.5 | Ref | Ref |
Yes | 3347 | 88,641 | 37.8 | 1.26 (1.20–1.32) | 1.19 (1.13–1.25) |
Sex | |||||
Women | 5129 | 147,980 | 34.7 | 1.24 (1.16–1.32) | 1.24 (1.16–1.32) |
Men | 1245 | 43,140 | 28.9 | Ref | Ref |
Age, years | |||||
18–39 | 1877 | 70,076 | 26.8 | Ref | Ref |
40–59 | 2907 | 76,051 | 38.2 | 1.40 (1.32–1.48) | 1.32 (1.24–1.40) |
≥ 60 | 1590 | 44,992 | 35.3 | 1.23 (1.15–1.32) | 1.05 (0.97–1.14) |
Comorbidity | |||||
Diabetes | |||||
No | 5777 | 175,900 | 32.8 | Ref | Ref |
Yes | 597 | 15,220 | 39.2 | 1.13 (1.04–1.23) | 0.97 (0.89–1.06) |
Obesity | |||||
No | 6319 | 190,127 | 33.2 | Ref | Ref |
Yes | 55 | 994 | 55.4 | 1.59 (1.22–2.08) | 1.42 (1.09–1.85) |
Osteoarthrosis | |||||
No | 5061 | 166,388 | 30.4 | Ref | Ref |
Yes | 1313 | 24,732 | 53.1 | 1.65 (1.55–1.75) | 1.51 (1.41–1.62) |
Sleep disorder | |||||
No | 4919 | 162,811 | 30.2 | Ref | Ref |
Yes | 1455 | 28,309 | 51.4 | 1.61 (1.52–1.71) | 1.36 (1.27–1.44) |
Irritable bowel syndrome | |||||
No | 5928 | 182,358 | 32.5 | Ref | Ref |
Yes | 446 | 8762 | 50.9 | 1.50 (1.37–1.66) | 1.25 (1.13–1.38) |
Migraine | |||||
No | 6100 | 186,279 | 32.8 | Ref | Ref |
Yes | 274 | 4841 | 56.6 | 1.67 (1.48–1.89) | 1.33 (1.18–1.51) |
TMJ | |||||
No | 6330 | 190,150 | 33.3 | Ref | Ref |
Yes | 44 | 970 | 45.4 | 1.32 (0.98–1.77) | 1.08 (0.80–1.46) |
Depression | |||||
No | 6025 | 184,138 | 32.7 | Ref | Ref |
Yes | 349 | 6982 | 50.0 | 1.46 (1.31–1.63) | 1.08 (0.96–1.21) |
Anxiety | |||||
No | 5864 | 181,973 | 32.2 | Ref | Ref |
Yes | 510 | 9147 | 55.8 | 1.64 (1.49–1.79) | 1.19 (1.08–1.31) |
