Table 3 Incidence density and hazard ratios of fibromyalgia according to iron deficiency anemia status stratified by sex, age, and comorbidity.

Variables	IDA group			Non-IDA group			HR (95% CI)
Variables	Event no	Person-year	Incidence density^#	Event no	Person-year	Incidence density^#	Crude	Adjusted^†
Sex
Women	2761	69,994	39.5	2368	77,986	30.4	1.28 (1.21–1.36)	1.22 (1.15–1.29)
Men	586	18,647	31.4	659	24,493	26.9	1.14 (1.02–1.27)	1.06 (0.94–1.18)
Age, years
18–39	1079	33,962	31.8	798	36,114	22.1	1.43 (1.30–1.56)	1.34 (1.22–1.47)
40–59	1531	35,731	42.9	1376	40,320	34.1	1.24 (1.15–1.33)	1.15 (1.07–1.24)
≥ 60	737	18,948	38.9	853	26,045	32.8	1.15 (1.04–1.27)	1.08 (0.98–1.19)
Comorbidity status^‡
No	1586	53,571	29.6	1769	72,980	24.2	1.22 (1.14–1.30)	1.22 (1.14–1.30)
Yes	1761	35,070	50.2	1258	29,499	42.7	1.16 (1.08–1.25)	1.15 (1.07–1.24)

IDA iron deficiency anemia, HR hazard ratio, CI confidence interval.
^#Per 1000 person-years.
^†Model mutually adjusted for sex, age, and each comorbidity (including diabetes, obesity, osteoarthrosis, sleep disorder, irritable bowel syndrome, migraine, TMJ, depression, and anxiety).
^‡Patients with any one of diabetes, obesity, osteoarthrosis, sleep disorder, irritable bowel syndrome, migraine, TMJ, depression, and anxiety were classified as the comorbidity group.

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