Table 1 Patients’ clinical characteristics and treatment details.
From: First Asian population study of stereotactic body radiation therapy for ventricular arrhythmias
Variable | Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | Patient 6 | Patient 7 |
|---|---|---|---|---|---|---|---|
Clinical characteristics | |||||||
Age (years) | 58 | 56 | 49 | 47 | 23 | 72 | 80 |
Sex | Female | Male | Male | Male | Male | Male | Male |
Indication | Ischemic cardiomyopathy | Dilated cardiomyopathy | Frequent PVCs | Dilated cardiomyopathy | Arrhythmogenic right ventricular cardiomyopathy | Hypertrophic cardiomyopathy | Dilated cardiomyopathy |
LVEF before treatment (%) | 45 | 20 | 66 | 30 | 69 | 42 | 43 |
Anti-arrhythmic drugs | Amiodarone | BB + amiodarone | BB + mexiletine | BB + amiodarone | BB + amiodarone | BB + amiodarone | BB + amiodarone |
Amiodarone dosage (mg/d) | 300 | 400 | 0 | 100 | 400 | 400 | 200 |
No. of catheter ablations | 1 | 0 | 2 | 1 | 4 | 2 | 2 |
No. of episodes of VT at 3 months before treatment | 34 | 14 | PVC 35% | 3 | 6 | 3 | 31 |
No. of ICD shocks | 5 | 3 | – | 1 | 6 | 2 | 8 |
Treatment | |||||||
Target region | Inferoposterior wall | Anterior wall | Basal anteroseptum | RVOT | RV basal septum | Apex | Anteroseptum to inferoseptum |
Volume (cm3) | |||||||
ITV | 15.4 | 40.9 | 9.4 | 4.6 | 11.5 | 35.3 | 33.5 |
PTV | 52.1 | 80.5 | 23.9 | 14.4 | 34.4 | 83.4 | 92.6 |
Time (min) | 12.7 | 17.3 | 14.4 | 9.2 | 10.9 | 12.5 | 12.5 |
No. of episodes of VT after treatment | 9 | 1 | PVC 0.2% | 0 | 13 | 5 | 0 |
No. of ICD shocks after treatment | 1 | 0 | – | 0 | 0 | 0 | 0 |
Time to recurrence (days) | 245 | 366 | – | 0 | 105 |  |  |
LVEF after treatment (%) | 33 | 22 | 72 | 68 | 65 | 42 | 33 |
