Table 1 Univariate and multivariate Cox proportional hazard analysis for disease-free survival of CCA patients.

From: Tumor necroptosis is correlated with a favorable immune cell signature and programmed death-ligand 1 expression in cholangiocarcinoma

Factor

Univariate

Multivariate

95% CI

HR

p-value

95% CI

HR

p-value

Gender

0.745

2.177

1.274

0.376

    

Age (MED = 67 years)

0.797

2.602

1.440

0.227

    

Type

1.322

4.173

2.349

0.004

0.255

15.347

1.979

0.514

HistoGradeEU

0.188

1.040

0.442

0.061

    

Tumor size (MED = 35 mm)

0.842

2.703

1.508

0.167

    

RIPK3 (MEDH-Score = 160)

0.883

2.507

1.488

0.136

    

MLKL (MEDH-Score = 120)

1.135

3.950

2.117

0.018

1.106

3.872

2.070

0.023

Vascular invasion

0.273

0.848

0.481

0.011

0.586

33.958

4.461

0.149

Neural/perineural invasion

0.354

1.102

0.625

0.104

    

Lymph node invasion

0.364

1.110

0.636

0.111

    

TNM stage

0.547

1.625

0.942

0.831

    
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