Figure 1

Protein clusters of acid dentin lysate (ADL). The STRING network shows proteins with at least three detectable peptides. Different line colors represent the types of evidence for the association between proteins. Based on kmean clustering method, network is categorized into four groups. There is a clear clustering of the histones and ribosomal proteins shown as yellow bubbles, and of five keratins shown as green bubbles. Not so sharp is the clustering of the collagens and other members of the extracellular matrix, some growth factors, chemokines and proteases. Network of interactions were depicted using String database (https://string-db.org).