Figure 1

XPCµT data acquired at the I13-2 beamline at the Diamond light XPCµT data acquired at the I13-2 beamline at the Diamond light source on lung tissue fragments embedded in paraffin. Brighter grey levels correspond to more absorbing (i.e. denser) material. For ease of view, the volumes are shown as projections on a plane of 300 slices, each 0.332 μm-thick (total thickness ~ 99 μm). In all images, several AB can be clearly identified as the white elongated object. (a) Sample A AB in are visible along with lung structures, such as bronchioles and alveoli. (b) Sample C an alveolar sac with AB accumulating on its walls, preferentially at its end, where hypercellularity occurs. (c) Sample D alveoli or bronchioles with AB penetrating the lung parenchyma. (d) Sample A magnification showing a variety of typical AB with sheatlike or beaded coatings. In all images, the scale bars are 100 μm long and the pixel size is 0.332 × 0.332 μm².