Table 2 Perioperative data.
Parameters | Control group (n = 25) | Dexmedetomidine group (n = 26) | P value |
|---|---|---|---|
Aneurysm/dissection/IMH or PAU | 10 (40)/14 (57)/1 (4) | 7 (27)/16 (62)/3 (12) | 0.428 |
Valve replacement | 1 (4.0) | 2 (7.7) | > 0.999 |
Aortic root replacement | 1 (4.0) | 1 (3.9) | > 0.999 |
Emergency | 15 (60) | 18 (69.23) | 0.491 |
Operation time (min) | 298 ± 63 | 311 ± 77 | 0.509 |
Total CPB time (min) | 170 ± 48 | 174 ± 45 | 0.760 |
ACC time (min) | 71 ± 41 | 83 ± 49 | 0.377 |
HCA time (min) | 50 ± 14 | 51 ± 14 | 0.820 |
Intraoperative input and output | |||
Crystalloid input (mL) | 2330 (1675–2700) | 1900 (1400–2425) | 0.214 |
Urine output (mL) | 1070 (600–1330) | 1435 (1165–1840) | 0.005* |
Cell saver transfused (mL) | 850 (733–1022) | 1000 (300–1245) | 0.627 |
pRBCs transfused (mL) | 250 (0–750) | 480 (0–750) | 1 |
FFP transfused (mL) | 733 ± 186 | 765 ± 190 | 0.545 |
Platelet transfused (mL) | 576 ± 177 | 560 ± 204 | 0.780 |
Intraoperative cardiovascular drugs | |||
Amount of norepinephrine (μg) | 360.0 (170.0–695.0) | 172.0 (40.0–344.0) | 0.027* |
Patients requiring vasopressin | 6 (24.0) | 7 (26.9) | 0.811 |
Patients requiring milrinone | 3 (12.0) | 5 (19.2) | 0.478 |
Amount of nicardipine (μg) | 0.0 (0.0–200) | 200.0 (0.0–1900) | 0.081 |
Postoperative 24 h input and output (mL) | |||
Crystalloid input (mL) | 4295 ± 1107 | 4046 ± 1178 | 0.441 |
Urine output (mL) | 3977 ± 1516 | 3706 ± 1222 | 0.484 |
Cell saver transfused (mL) | 0 (0–0) | 0 (0–213) | 0.183 |
pRBCs transfused (mL) | 0 (0–207) | 0 (0–0) | 0.543 |
FFP transfused, mL | 0 (0–575) | 0 (0–215) | 0.204 |
Platelet transfused (mL) | 0 (0–0) | 0 (0–0) | 1 |
Blood loss (mL) | 628 (495–887) | 640 (419–844) | 0.836 |
Postoperative 24 h cardiovascular drugs | |||
Patients requiring norepinephrine | 11 (44.0) | 12 (46.2) | 1.000 |
Amount of nicardipine (μg) | 796.0 (362.0–1591.0) | 324.0 (100.0–821.0) | 0.026* |
