Figure 6

Ingenuity pathway analysis (IPA) of the MGAM-related upstream regulator (A) and disease or functional annotations (B) in colon mucosa proteomes of internal BD and CD. IPA core analyses were performed for a proteomic comparison between internal BD and CD using 3,614 UniProt accession numbers. Significant MGAM-related functional annotations are shown (z-score > 2, p < 0.05). Heat maps illustrating the predicted activation z-score. The color range indicates its predicted activation state: increasing (orange) or decreasing (blue).