Figure 7
From: Lidocaine and bupivacaine as part of multimodal pain management in a C57BL/6J laparotomy mouse model
Nest complexity scores displayed for female and male mice for each treatment group. The blue arrow indicates that a new nestlet was provided for baseline measurements, the red arrow indicates the surgery/anesthesia followed by the distribution of a new nestlet. Bonferroni post hoc testing detected no significant differences between the treatment groups at baseline level and 3 h post-procedure. Male LiBupOP had a significantly higher nest complexity score than PaLiBupOP and PaOP 6 and 12 h post-procedure; at 24 h post-procedure male LiBupOP had a significantly higher score than all other treatment groups. In female mice, 24 h post-procedure nest complexity in LiBupOP was significantly higher than in all other treatment groups. Significant differences to respective baseline measurements are indicated with *p ≤ 0.05, Dunnett’s post hoc. Data are shown as scatter dot plot with mean ± SD. Numbers per group: PaLiBupOP, LiBupOP, PaOP, and PaAn n = 10/per sex.
