Table 3 Most highly up- or downregulated retinal transcripts in bTBI- vs. sham-treated mice at 5-weeks post injury detected by RNA sequencing.
From: Axonopathy precedes cell death in ocular damage mediated by blast exposure
Symbol | Description | Fold change | p-value | FDR |
|---|---|---|---|---|
Upregulated | ||||
Ecel1 | Endothelin converting enzyme-like 1/dine | 2.68 | 1.16E−06 | 2.10E−04 |
Lad1 | Ladinin | 1.78 | 3.48E−05 | 3.46E−03 |
Pros1 | Protein S, alpha | 1.37 | 3.04E−05 | 3.16E−03 |
Impg2 | Interphotoreceptor matrix proteoglycan 2 | 1.10 | 4.93E−05 | 4.67E−03 |
Downregulated | ||||
Cplx1 | Complexin 1 | 0.56 | 2.77E−13 | 4.40E−09 |
Nefm | Neurofilament, medium polypeptide | 0.56 | 2.67E−12 | 1.54E−08 |
Vamp1 | Vesicle-associated membrane protein 1 | 0.70 | 2.90E−12 | 1.54E−08 |
Rgs4 | Regulator of G-protein signaling 4 | 0.59 | 1.37E−11 | 5.46E−08 |
Thy1 | Thymus cell antigen 1, theta | 0.70 | 4.66E−11 | 1.39E−07 |
Coro6 | Coronin 6 | 0.53 | 5.59E−11 | 1.39E−07 |
Sncg | Synuclein, gamma | 0.59 | 6.12E−11 | 1.39E−07 |
Nefl | Neurofilament, light polypeptide | 0.60 | 8.63E−11 | 1.72E−07 |
Lynx1 | Ly6/Neurotoxin 1 | 0.77 | 1.11E−10 | 1.96E−07 |
Nefh | Neurofilament, heavy polypeptide | 0.62 | 1.42E−10 | 2.26E−07 |
