Figure 1 | Scientific Reports

Figure 1

From: Inhibition of epithelial–mesenchymal transition in retinal pigment epithelial cells by a retinoic acid receptor-α agonist

Figure 1

Inhibitory effect of an RAR-α agonist on RPE cell-mediated collagen gel contraction induced by TGF-β2. RPE cells were incubated in collagen gels with or without TGF-β2 (1 ng/ml) and the indicated concentrations (0 to 30 µM) of Am580 for 48 h (a) or with or without TGF-β2 (1 ng/ml) and Am580 (10 µM) for 0 to 48 h (b), after which the gel diameter was determined. Data are means ± s.d. from four independent experiments. *P < 0.05, **P < 0.01 (Dunnett’s test) versus the corresponding value for cells cultured with TGF-β2 alone.

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