Table 1 DETC antiparasitic activity, expressed in IC50 values ± standard deviation, against the different strains and forms of Trypanosoma cruzi after 24 h of exposure, based on results expressed by couting essay.

From: Insights of antiparasitic activity of sodium diethyldithiocarbamate against different strains of Trypanosoma cruzi

Trypanosoma cruzi strains (DTUs)

IC50 epimastigote

IC50 trypomastigote

DETC (μM)

BZN (μM)

DETC (μM)

BZN (μM)

Strain Dm28c (TcI)

37.13 ± 7.58a

78.12 ± 8.01a

40.12 ± 6.58a

91.95 ± 2.87b

Strain Y (TcII)

50.41 ± 3.56b

96.66 ± 5.38b

31.19 ± 7.21b

98.74 ± 3.98b

Strain QMM9 (TcIII)

60.15 ± 6.45b

101.38 ± 5.39b

46.76 ± 5.11a

103.47 ± 2.45c

Strain CL Brener (TcVI)

49.12 ± 5.78b

71.56 ± 7.98a

43.83 ± 4.55a

82.43 ± 5.83a

  1. The statistical analysis the Anova Test together with the Tukey Post-test. The statistical analysis used measure the IC50 value in each group under same conditions.
  2. BZN benznidazole.