Figure 3
From: The heavy chain of 4F2 antigen promote prostate cancer progression via SKP-2
4F2hc RNA-sequencing analysis. RNA-seq analysis was performed with si4F2hc (si4F2hc-1 and si4F2hc-2) and compared with a control group (A). The most down-regulated 1403 genes are selected, and Matascape is used for analysis of significantly related with GO terms (B). Si4F2hc concentration-dependent effect on candidate genes was assessed by real-time PCR (C). SiSKP2 (siSKP2-1 and siSKP2-2) inhibits C4-2 cell proliferation (D). Data represent three independent experiments with similar results. P-values were calculated by the Mann–Whitney U-test. *** p < 0.001.
