Figure 6

PAC suppresses the process of epithelial-to-mesenchymal transition and inhibits cell migration in oral cancer cells. (A) PAC at 5 µM inhibits the EMT in oral cancer cells by increasing E-cadherin expression, while vimentin expression was decreasing (n = 3). (B) Wound Healing (Scratch) Assay: after 6 h of treatment, PAC dose-dependent inhibits ca9-22 cell migration (n = 3). All Blots derive from the same experiment and were exposed at same time of phosphor imager exposition.