Table 2 Association between SU as a continuous variable and subsequent CVD and MACE events by sex, unadjusted and with minimal adjustment for age and mean DCCT/EDIC HbA1c.
From: Serum urate and cardiovascular events in the DCCT/EDIC study
Men (n = 540) | Women (n = 433) | |||||
|---|---|---|---|---|---|---|
No. of Participants (%)a | HR (95% CI)b p-value unadjusted | HR 95% CI)b p-value adjusted | No. of Participants (%)a | HR (95% CI)b p-value unadjusted | HR (95% CI)b p-value adjusted | |
Any cardiovascular disease event | 61 (11) | 1.18 (0.92–1.50) 0.1920 | 1.15 (0.90–1.46) 0.2717 | 49 (11) | 1.22 (0.93–1.60) 0.1544 | 1.17 (0.88–1.56) 0.2833 |
1. Non-fatal acute myocardial infarction | 16 (3) | 15 (3) | ||||
2. Non-fatal cerebrovascular event | 7 (1) | 7 (2) | ||||
3. Death from cardiovascular disease | 6 (1) | 5 (1) | ||||
4. Silent myocardial infarction | 13 (2) | 14 (3) | ||||
5. Confirmed angina | 6 (1) | 12 (3) | ||||
6. Revascularization | 37 (7) | 22 (5) | ||||
7. Congestive heart failure | 3 (1) | 1 (< 1) | ||||
Non-fatal MI or stroke or death from cardiovascular disease (MACE) | 29 (5) | 1.13 (0.79–1.61) 0.5083 | 1.10 (0.77–1.58) 0.5944 | 24 (6) | 1.52 (1.07–2.16) 0.0211 | 1.47 (1.01–2.14) 0.0466 |
1. Non-fatal acute myocardial infarction | 16 (3) | 15 (3) | ||||
2. Non-fatal cerebrovascular event | 7 (1) | 7 (2) | ||||
3. Death from cardiovascular disease | 6 (1) | 5 (1) | ||||