Figure 3 | Scientific Reports

Figure 3

From: Additional partial hepatectomy at the time of portal vein ligation accelerates the regeneration of the future liver remnant

Figure 3

BrdU-staining, hepatocyte proliferation index (PI), PCNA mRNA expression level of the non-ligated FLR. (a) Immunohistochemistcal analysis of BrdU incorporation of non-ligated FLR on POD2. More BrdU-positive cells were observed after simultaneous PVL and PHx compared with PVL alone (Scale marker: 100 μm, magnification: ×200). (b) Proliferation index (PI) in the non-ligated FLR was significantly higher on POD2 after additional large PHx and additional small PHx compared with PVL alone (PI: 15% vs 6%, 12% vs 6%, *p value < 0.05). (c) PCNA mRNA expression level in the FLR was substantially increased after additional PHx compared with PVL alone (fold change: 11 vs 8.4 vs 6.7, *p < 0.05).

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