Table 2 Comparative analysis of clinical and therapeutic parameters according to the subsequent achievement of VRE negative conversion.

From: A Japanese traditional medicine Hochuekkito promotes negative conversion of vancomycin-resistant Enterococci

 

Subsequent achievement of VRE negative conversion

p-value

Yes (n = 39)

No (n = 83)

Male:Female (n)

23:16

50:33

0.8941

Age (years)*

71.9 ± 12.4 years

72.1 ± 14.0 years

0.9552

Body mass index at hospitalization*

23.22 ± 4.85

21.93 ± 4.09

0.1491

Serum albumin level at hospitalization*

3.37 ± 0.85 g/dL

3.02 ± 0.79 g/dL

0.0310

Past medical history

Diabetes mellitus, n (%)

10 (25.6%)

28 (33.7%)

0.3680

Hypertension, n (%)

17 (43.6%)

33 (39.8%)

0.6883

Dyslipidemia, n (%)

7 (17.9%)

6 (7.2%)

0.1125

Details of treatment after admission before VRE detection

Perioperative case (n; surgery after admission [%])

10 (25.6%)

18 (21.7%)

0.6281

Use of antibiotics (total; n [%])

34 (87.2%)

76 (91.6%)

0.5186

Use of antibiotics (VCM; n [%])

6 (15.4%)

20 (24.1%)

0.3466

Use of a nasogastric feeding tube, n (%)

21 (53.8%)

33 (39.8%)

0.1440

Details of the treatment for VRE

Probiotics, n (%)

29 (74.4%)

40 (48.2%)

0.0065

Total Kampo medicines, n (%)

13 (33.3%)

5 (6.0%)

0.0002

Hochuekkito, n (%)

11 (28.2%)

5 (6.0%)

0.0014

  1. Kampo medicines (total) means hochuekkito (n = 16), juzentaihoto (n = 1), and ninjin'yoeito (n = 1).
  2. VCM vancomycin, VRE vancomycin-resistant enterococcus.
  3. *Mean and standard deviation.