Table 4 Univariate and multivariate linear mixed model determination of factors associated with changes in the best-corrected visual acuity (BCVA).
From: Changes in each retinal layer and ellipsoid zone recovery after full-thickness macular hole surgery
Univariate | Multivariate (model 1) | Multivariate (model 2) | ||||
|---|---|---|---|---|---|---|
Estimate (95% CI) | P value | Estimate (95% CI) | P value | Estimate (95% CI) | P value | |
Age | − 0.006 (− 0.021–0.010) | 0.461 | ||||
Sex | − 0.293 (− 0.579 to − 0.006) | 0.046 | 0.044 (− 0.139–0.228) | 0.627 | 0.023 (− 0.157–0.213) | 0.762 |
Diabetes | 0.051 (− 0.327–0.429) | 0.783 | ||||
Hypertension | − 0.079 (− 0.372–0.215) | 0.587 | ||||
Axial length | 0.001 (− 0.001–0.002) | 0.667 | ||||
Combined surgery | − 0.144 (− 0.449–0.160) | 0.340 | ||||
Baseline BCVA | 0.701 (0.486–0.915) | < 0.001 | 0.442 (0.154–0.669) | 0.003 | 0.424 (0.165–0.683) | 0.002 |
F/U duration after surgery | − 0.033 (− 0.045 to − 0.021) | < 0.001 | − 0.128 (− 0.025 to − 0.001) | 0.034 | − 0.014 (− 0.026 to − 0.002) | 0.025 |
Stage of MH | 0.102 (− 0.124–0.326) | 0.364 | ||||
MLD | 0.002 (0.001–0.002) | < 0.001 | 0.001 (< 0.001–0.002) | 0.025 | 0.001 (< 0.001–0.002) | 0.034 |
Base diameter | 0.001 (< 0.001–0.001) | 0.012 | < 0.001 (− 0.001–0.001) | 0.954 | < 0.001 (− 0.001–0.001) | 0.810 |
Recovery of ELM | 0.018 (− 0.143–0.179) | 0.824 | ||||
Recovery of ONL | 0.088 (− 0.023–0.199) | 0.121 | ||||
Recovery of EZ | 0.240 (0.142–0.338) | < 0.001 | 0.122 (0.032–0.213) | 0.008 | 0.121 (0.028–0.214) | 0.011 |
Subfoveal thickness | 0.002 (0.002–0.003) | < 0.001 | 0.002 (0.001–0.003) | < 0.001 | ||
IRL thickness | 0.003 (0.002–0.003) | < 0.001 | 0.002 (0.002–0.003) | < 0.001 | ||
ORL thickness | < 0.001 (− 0.003–0.003) | 0.982 | ||||
PRL thickness | − 0.015 (− 0.023 to − 0.006) | 0.001 | − 0.001 (− 0.013–0.001) | 0.128 | − 0.001 (− 0.015–< 0.001) | 0.061 |
