Table 2 Impact of VI on the risk of dementia via multivariable time-varying Cox regression analyses.

From: Visual impairment increases the risk of dementia, especially in young males in a 12-year longitudinal follow-up study of a national cohort

Variables

Model 1a

Model 2b

HR (95% CI)

p value

HR (95% CI)

p value

VI (yes)

1.559 (1.479–1.644)

< 0.0001

2.726 (2.251–3.300)

< 0.0001

Age group (≥ 65 years)

10.587 (9.867–11.360)

< 0.0001

12.069 (10.674–13.646)

< 0.0001

Sex (female)

1.522 (1.453–1.594)

< 0.0001

1.406 (1.193–1.657)

< 0.0001

VI* age group (yes, ≥ 65 years)

  

0.539 (0.436–0.667)

< 0.0001

VI* sex (yes, female)

  

0.986 (0.749–1.300)

0.9219

Age group* sex (≥ 65 years, female)

  

1.106 (0.929–1.316)

0.2578

VI* age group* sex (yes, ≥ 65 years, female)

  

0.972 (0.720–1.312)

0.8540

  1. VI = visual impairment; CI = confidence interval; HR = hazard ratio.
  2. aAdjusted for age and sex.
  3. bAdjusted for age, sex and all interactions between age, sex and VI.