Figure 1
Differences in the circRNA expression profile between Sham and ICH groups. (A) Volcano plot showed differential expression of circRNAs between Sham and ICH groups on the 7th day. (B) Volcano plot showed differential expression of circRNAs between Sham and ICH groups on the 28th day. (C) PCA plot revealed the discrimination between day-7 and day-28 samples. (D) Top 10 differentially downregulated and top 10 differentially upregulated circRNAs, in ICH samples, on days 7 and 28, respectively. The horizontal line in the volcano map represented the fold (log2 scaled) down or up changes; the vertical line represented a corrected P value of 0.05 (-log10 scaled); green spots indicated the differentially down-expressed RNAs with statistical significance; red spots indicated the differentially up-expressed RNAs with statistical significance; blue spots indicated RNAs with no statistically significant expression. The variances explained by the principal components chosen were shown as PC1 and PC2.
