Figure 5 | Scientific Reports

Figure 5

From: Native mass spectrometry analyses of chaperonin complex TRiC/CCT reveal subunit N-terminal processing and re-association patterns

Figure 5

Updated conceptual workflow for solution dissociation coupled to native mass spectrometry. The highlighted arrow from Complete disassembly to Oligomers represents the novel pathway observed in this study, which can occur if, for example, subunits possess moonlighting functions with alternative partners or are paralogous and retain non-canonical interface compatibility. Assignment of contacts as canonical or non-canonical ensures that native MS is appropriately applied in integrative structural biology pipelines.

Back to article page