Table 1 List of genes related to cell cycle displayed significant differential expression between asthmatic and healthy epithelium in both genders, bronchial brush versus the biopsy sample, and between asthmatic and healthy fibroblasts, from publicly available datasets (GSE64913, GSE76227, and GSE27335).
Genes | Number of enriched pathways | Gender | Biopsy vs brush | In asthmatic epithelium | In asthmatic fibroblasts |
|---|---|---|---|---|---|
ABCA1 | 117 | Both | Both | Upregulated | Upregulated |
GPRC5A | 108 | Both | Both | Upregulated | Upregulated |
KRT8 | 106 | Both | Both | Upregulated | Upregulated |
SFN | 102 | Both | Both | Upregulated | Upregulated |
TOP2A | 175 | Both | Both | Upregulated | Downregulated |
MKI67 | 171 | Both | Both | Upregulated | Downregulated |
RRM2 | 147 | Both | Both | Upregulated | Downregulated |
ANLN | 109 | Both | Both | Upregulated | Downregulated |
NEK2 | 108 | Both | Both | Upregulated | Downregulated |
SERPINE1 | 103 | Both | Both | Upregulated | Downregulated |
