Figure 1 | Scientific Reports

Figure 1

From: Microarray analysis reveals ONC201 mediated differential mechanisms of CHOP gene regulation in metastatic and nonmetastatic colorectal cancer cells

Figure 1

Response of Dukes' type B colorectal adenocarcinoma cell lines to ONC201 treatments. (A) Dose-dependent response of metastatic LS-174T and nonmetastatic SW480 cells to ONC201 treatment. Cells were plated in a 96-well plates, cell viability was assayed by MTT and detected using spectrophotometer. (B) Flow cytometric analysis of LS-174T and SW480 cells treated with or without 10 μM ONC201 for 48 h. Apoptotic cells were detected using annexin V kit, values are expressed as mean ± SD. Significant values were set as *P < 0.01 (n = 3 each in duplicates).

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